Drug Uses

Aciphex decreases the amount of acid produced in your stomach. Aciphex is used to treat ulcers, gastroesophageal reflux disease (GERD or heartburn), and other conditions involving excessive stomach acid production.

How Taken

Aciphex is available for oral administration as delayed-release, enteric-coated tablets. The recommended adult oral dose is one Aciphex 20 mg delayed-release tablet to be taken once daily for four to eight weeks. Take each dose with a full glass of water. Do not break, chew, or split the tablets. Swallow them whole. They are specially formulated to release slowly in your body.

Warnings/Precautions

Before taking Aciphex, tell your doctor if you are taking any of the following medicines: ketoconazole (Nizoral), ampicillin (Omnipen, Principen), iron (Feosol, Mol-Iron, Fergon, Femiron, others), digoxin (Lanoxin, Lanoxicaps), or cyclosporine (Sandimmune, Neoral). You may not be able to take Aciphex, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with Aciphex. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Possible Side Effects

Serious side effects from Aciphex are rare. Stop taking Aciphex and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives) to Aciphex. Less serious side effects from Aciphex are also uncommon. Continue to take Aciphex and talk to your doctor if you experience headache; upset stomach or diarrhea; insomnia or nervousness; or a rash or itching. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Keep Aciphex out of the reach of children. Store Aciphex at room temperature (between 59°F and 86°F). Protect Aciphex from moisture.

Overdose

Symptoms of an Aciphex overdose are not known. Seek emergency medical attention.

More Information

There are no restrictions on food, beverages, or activity while taking Aciphex, unless otherwise directed by your doctor. Do not stop taking Aciphex even if you begin to feel better. Your symptoms may improve before your condition is fully treated.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Understanding Heartburn -- Treatment

What Are the Treatments?
To determine an effective heartburn treatment, you doctor needs to learn about your heartburn. Your description of your heartburn symptoms may be all a doctor requires, but sometimes additional procedures are necessary. The esophagus can be viewed through an endoscope -- a long, thin, flexible tube inserted through the mouth -- or by X-ray.
Over-the-counter antacids are commonly prescribed to neutralize stomach acid. If antacids don't quell the symptoms, your doctor may recommend an over-the-counter heartburn drug such as Pepcid AC, Tagamet HR, Axid AR, or Zantac 75.
If heartburn symptoms persist, your doctor can turn to drugs such as Prevacid, Prilosec, Nexium, Protonix, or Aciphex to reduce the stomach's production of acid, or Reglan to make the stomach empty itself faster.
When all else fails, surgery may be required to repair the lower esophageal sphincter. This surgery can now be done using a laparoscope and requires only a short hospital stay.
Lifestyle Changes to Manage Your Heartburn
Remember, diet does NOT cause GERD. Nevertheless, GERD and its most frequent symptom of heartburn can be aggravated by foods, certain medications and other factors. Here are some suggestions to improve your heartburn symptoms.
* Don't go to bed with a full stomach. Eat meals at least two to three hours before lying down -- this will give food time to digest and empty from your stomach, and acid levels a chance to decrease before putting your body in a position where heartburn is more likely to occur.
* Don't overeat. Decrease the size of portions at meal times, or try eating four to five small meals instead of three large ones.
* Eat slowly. Take time to eat -- don't rush. Try putting your fork down between bites.
* Wear looser-fitting clothes.
* Avoid heartburn triggers. Stay away from foods and beverages that trigger your heartburn symptoms (for example, onions, peppermint, chocolate, caffeine-containing beverages such as coffee, citrus fruits or juices, tomatoes, or high-fat foods). A good way to figure out what foods cause your symptoms is to keep a heartburn diary.
* Shed some pounds. If you are overweight, losing weight can help relieve your symptoms.
* Stop smoking. Nicotine, one of the main active ingredients in cigarettes, can weaken the lower esophageal sphincter, the muscle that controls the opening between the esophagus and stomach, preventing the acid-containing contents of the stomach from entering the esophagus.
* Avoid alcohol. If your aim is to unwind after a stressful day, try exercise, walking, meditation, stretching, or deep breathing instead of drinking alcohol.
* Keep a diary or heartburn log. Keep track of when heartburn hits and the specific activities that seem to trigger the incidents.
If Your Heartburn Is Worse When Lying Down:
Raise the head of your bed so that your head and chest are higher than your feet. You can do this by placing six-inch blocks under the bed posts at the head of the bed. Don't use piles of pillows to achieve the same goal. You will only put your head at an angle that can increase pressure on your stomach and make your heartburn worse.
* Eat earlier. Try not to eat for at least three hours before you go to sleep.
If Your Heartburn Worsens After Exercise:
* Time your meals. Wait at least two hours after a meal before exercising. If you work out any sooner, you may trigger heartburn.
* Drink more water. Drink plenty of water before and during exercise to prevent dehydration.

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