Drug Uses
Colchicine is used to treat attacks of gout.
How Taken
Take each dose of Colchicine with a full glass of water. You may take this medicine up to once every hour until the pain is relieved, until the maximum amount of medicine has been taken, or until nausea, vomiting, or diarrhea occurs. To prevent an attack from occurring, you may take Colchicine every day or several days a week. Do not take more doses than your doctor prescribed.
Warnings/Precautions
Do not take Colchicine without first talking to your doctor if you are breast-feeding a baby. Talk to your doctor if you are or plan on becoming pregnant as this medicine may have harmful effects on the unborn baby.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Some of the side effects that may occur while taking Colchicine include: difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; fever; rash; numbness or tingling.
Storage
Store Colchicine at room temperature away from moisture and heat. Keep out of the reach of children.
Overdose
Symptoms of a colchicine overdose include nausea; vomiting; stomach pain; diarrhea; muscle weakness; burning in your throat, stomach, or skin; difficulty breathing; delirium; and seizures. An overdose of colchicine can result in death. If you suspect an overdose, seek immediate medical attention.
More Information
Tell your doctor and pharmacist about all medicines that you are taking. Colchicine may interact with other drugs.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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People who have symptoms of arthritis are often prescribed one of the non-selective, nonsteroidal anti-inflammatory drugs (NSAIDs) or one of the newer group of NSAIDS known as cyclo-oxygenase-2 inhibitors (COX-2 selective inhibitors).
Non-selective NSAIDs have been associated with an increased risk of congestive heart failure. Less is known or has been concluded about the cardiovascular effects of COX-2 selective inhibitors.
The Lancet (2004;363:1751-56) has revealed results of a Canadian study involving over 130,000 older people. Muhammad Mamdani from the Institute for Clinical Evaluative Sciences, Toronto, Canada, and colleagues did a retrospective analysis of the risk of hospital admission for heart failure for around:
* 14,500 people using the COX-2 inhibitor Vioxx (rofecoxib)
* 19,000 people using the COX-2 inhibitor Celebrex (celecoxib)
* 5,400 people using non-selective NSAIDs
* 100,000 people not using any NSAID served as the control group
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