Drug Uses

Diflucan is indicated for the treatment of:
-Vaginal candidiasis (vaginal yeast infections due to Candida).
-Oropharyngeal and esophageal candidiasis.
-Cryptococcal meningitis.
Diflucan is also indicated to decrease the incidence of candidiasis in patients undergoing bone marrow transplantation who receive cytotoxic chemotherapy and/or radiation therapy.

How Taken

Diflucan comes as a tablet and liquid to take by mouth. It is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Diflucan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well before each use to mix the medication evenly. Continue to take Diflucan even if you feel well. Do not stop taking Diflucan without talking to your doctor.

Warnings/Precautions

Do not take Diflucan if you are taking cisapride (Propulsid). Combined with cisapride (Propulsid), Diflucan could cause serious, even fatal, heart problems. Before taking Diflucan, tell your doctor if you have any other medical conditions, especially kidney disease, or if you take other medicines. You may not be able to take Diflucan, or you may require a dosage adjustment or special monitoring during your treatment. Diflucan is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take Diflucan without first talking to your doctor if you are pregnant or could become pregnant during treatment. Diflucan passes into breast milk and may be harmful to a nursing baby. For this reason, Diflucan should not be taken by nursing mothers. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects

If you experience any of the following serious side effects, stop taking Diflucan and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); liver damage (pale stools, yellowing of the skin or eyes, abdominal pain, unusual fatigue, or dark urine); or a rash. Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue taking Diflucan and talk to your doctor: nausea, vomiting, or abdominal pain; diarrhea; headache; dizziness; fatigue; or itching. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store tablets below 86°F (30°C). Protect from freezing. Diflucan injections in Viaflex Plus plastic containers are available in both sodium chloride and dextrose diluents. Store between 77°F (25°C) and 41°F (5°C). Brief exposure up to 104°F (40°C) does not adversely affect the product. Protect from freezing.

Overdose

Seek emergency medical attention if an overdose is suspected. Symptoms of a Diflucan overdose include confusion, hallucinations, paranoia, decreased movement, decreased breathing, tearing eyes, drooling, urinary incontinence, seizures, and death.

More Information

Avoid alcohol or use it in moderation while taking Diflucan. Alcohol and Diflucan can both affect the liver. Use caution when driving or performing other hazardous activities. Diflucan may cause dizziness. If you experience dizziness, avoid these activities.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Menopause is the transition period in a woman's life when her ovaries stop producing eggs, her body produces less estrogen and progesterone, and menstruation becomes less frequent, eventually stopping altogether. Causes, incidence, and risk factors Menopause is a natural event that normally occurs between the ages of 45 and 55. Once menopause is complete (called postmenopause), you can no longer become pregnant. The symptoms of menopause are caused by changes in estrogen and progesterone levels. As the ovaries become less functional, they produce less of these hormones and the body responds accordingly. The specific symptoms you experience and how significant (mild, moderate, or severe) varies from woman to woman. In some women, menstrual flow comes to a sudden halt. More commonly, it tapers off. During this time, your menstrual periods generally become either more closely or more widely spaced. This irregularity may last for 1 to 3 years before menstruation finally ends completely. A gradual decrease of estrogen generally allows your body to slowly adjust to the hormonal changes. When estrogen drops suddenly, as is seen when the ovaries are removed surgically (called surgical menopause), symptoms can be more severe. Because hormone levels fall, changes occur in the entire female reproductive system. The vaginal walls become less elastic and thinner. The vagina becomes shorter. Lubricating secretions from the vagina become watery. The outside genital tissue decreases. This is called atrophy of the labia. Symptoms The potential symptoms include: * Hot flashes and skin flushing * Night sweats * Insomnia * Mood swings including irritability, depression, and anxiety * Irregular menstrual periods * Spotting of blood in between periods * Vaginal dryness and painful sexual intercourse * Decreased sex drive * Vaginal infections * Urinary tract infections In addition, the long-term effects of menopause include: * Bone loss and eventual osteoporosis * Changes in cholesterol levels and greater risk of heart disease Signs and tests Blood and urine tests can be used to measure hormone levels that may indicate when a woman is close to menopause or has already gone through menopause. Examples of these tests include: * Estradiol * FSH * LH A pelvic exam may indicate changes in the vaginal lining caused by changes in estrogen levels. A bone density test may be performed to screen for low bone density levels seen with osteoporosis. Treatment Menopause is a natural process. It does not require treatment unless the symptoms, such as hot flashes or vaginal dryness, are particularly bothersome. One big decision you may face is whether or not to take hormones to relieve your symptoms. Discuss this thoroughly with your doctor, weighing your risks against any possible benefits. Pay careful attention to the many options currently available to you that do not involve taking hormones. If you have a uterus and decide to take estrogen, you must also take progesterone to prevent endometrial cancer (cancer of the lining of the uterus). If you do not have a uterus, progesterone is not necessary. HORMONE REPLACEMENT THERAPY For years, hormone replacement therapy (HRT) was the main treatment for menopause symptoms. Many physicians believed that HRT was not only good for reducing menopausal symptoms, but also reduced the risk of heart disease and bone fractures from osteoporosis . However, the results of a major study -- called the Women's Health Initiative -- has led physicians to revise their recommendations. In fact, this important study was stopped early because the health risks outweighed the health benefits. Women taking the hormones did see some benefits. But they greatly increased their risk for breast cancer, heart attacks, strokes, and blood clots. If your symptoms are severe, you may still want to consider HRT for short-term use (2-4 years) to reduce vaginal dryness, hot flashes, and other symptoms. To reduce the risks of estrogen replacement therapy and still gain the benefits of the treatment, your doctor may recommend: * Using estrogen/progesterone regimens that do not contain the form of progesterone used in the study. * Using a lower dose of estrogen or a different estrogen preparation (for instance, a vaginal cream rather than a pill). * Having frequent and regular pelvic exams and Pap smears to detect problems as early as possible. * Having frequent and regular physical exams, including breast exams and mammograms. ALTERNATIVES TO HRT The good news is that you can take many steps to reduce your symptoms without taking hormones: * Dress lightly and in layers * Avoid caffeine, alcohol, and spicy foods * Practice slow, deep breathing whenever a hot flash starts to come on (try taking six breaths per minute) * See an acupuncturist * Use relaxation techniques like yoga, tai chi, or meditation * Eat soy foods * Remain sexually active to preserve elasticity of your vagina * Perform Kegel exercises daily to strengthen the muscles of your vagina and pelvis * Use water-based lubricants during sexual intercourse There are also some medications available to help with mood swings, hot flashes, and other symptoms. These include low doses of antidepressants such as paroxetine (Paxil), venlafaxine (Effexor), bupropion (Wellbutrin), and fluoxetine (Prozac), or clonidine, which is normally used to control high blood pressure.

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