Drug Uses

Vermox is used to treat threadworms and other common worm infections.

How Taken

Take Vermox orally. Your doctor will tell you how much Vermox to take and for how long you should continue to take it. Always read the label on your medicine and follow your doctor's instructions carefully.

Warnings/Precautions

Do not give Vermox to children younger than 2 years of age. If you are or think you may be pregnant, do not take Vermox. Talk to your doctor first. The active ingredient in Vermox may get into breast milk, so it is therefore not advisable to breast feed while you are taking Vermox.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Possible Side Effects

You may experience minor adverse reactions such as mild, short-lived stomach ache or diarrhoea, or possibly an allergic reaction such as rash, shortness of breath, itching etc.

Storage

Keep Vermox in a safe place where children cannot reach or see them. Do not store above 25°C. Protect from light. Do not use the medicine after the expiry date printed on the blister and carton.

Overdose

If you or another person has taken too much Vermox, talk to your doctor as soon as possible, telling him what has happened.

More Information

There are no restrictions on foods, beverages or performing other activities while taking Vermox.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Nifurtimox and eight structurally related 5-nitrofuran compounds active against Trypanosoma cruzi were tested for genotoxicity in the wing somatic mutation and recombination test in Drosophila melanogaster. Nifurtimox, compound ada and compound 1B were clearly mutagenic and recombinogenic whereas the remaining six compounds were negative. In contrast to the situation in bacterial mutagenicity tests, nitroreductase activity is probably not decisive for the genotoxicity of these compounds in Drosophila. The three non-genotoxic nitrofurans with high antiparasitic activity are promising candidates for the replacement of nifurtimox. However, these compounds require further genotoxicity testing in eukaryotic assay systems for a final evaluation.

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