Drug Uses
Zyloprim reduces the production of uric acid in your body. Zyloprim is used to treat gout, increased levels of uric acid caused by cancer treatment, and kidney stones that are caused by high levels of uric acid.
How Taken
Zyloprim comes as a tablet to take it orally. It usually is taken once a day, preferably after a meal. Drink at least eight glasses of water or other fluids each day while taking Zyloprim unless directed to do otherwise by your doctor. Avoid excessive amounts of vitamin C supplements or fruit juice while taking Zyloprim. Too much vitamin C may increase your chance of developing kidney stones.
Warnings/Precautions
Before taking Zyloprim, tell your doctor if you have kidney or liver disease. You may need a lower dose of Zyloprim or special monitoring during your therapy.
Zyloprim is in the FDA pregnancy category C. This means that it is not known whether Zyloprim will harm an unborn baby. Do not take Zyloprim without first talking to your doctor if you are pregnant.
Zyloprim passes into breast milk. Do not take Zyloprim without first talking to your doctor if you are breast-feeding a baby.
Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.
Possible Side Effects
If you experience any of the following serious side effects, stop taking Zyloprim and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); blood in your urine or pain when you urinate; a rash; eye irritation; fever, chills, or joint aches; or severe nausea or vomiting.
Other, less serious side effects may be more likely to occur. Continue to take Zyloprim and talk to your doctor if you experience upset stomach or diarrhea; headache, dizziness, or drowsiness; or an acute attack of gouty arthritis.
Side effects other than those listed here may also occur. Talk to your doctor about any reaction that seems unusual or that is especially bothersome.
Storage
Store at 15-25°C (59-77°F) in a dry place and protect from light.
Overdose
Seek emergency medical attention. Symptoms of Zyloprim overdose are not known.
More Information
Use caution when driving, operating machinery, or performing other hazardous activities. Zyloprim may cause drowsiness. If you experience drowsiness, avoid these activities.
Avoid alcohol. It may worsen your condition.
Follow your doctor's recommendations about diet.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Disability and a recent diagnosis of rheumatoid arthritis (RA) are associated with a greater risk for depression according to research funded by the Arthritis Foundation.
Studies show that people with RA who are depressed have worse outcomes including death as compared to people with RA who are not depressed. Previous studies regarding RA and depression included a primarily Caucasian population. To remedy this bias, scientists from University of California, San Francisco, designed a study to evaluate predictors of depression in patients from a multiethnic group of people with RA at an urban hospital.
Of the 210 people with RA enrolled in the study, 39 percent had scores on the Patient Health Questionnaire-9 that indicated at least moderate depression. Patient-, disease-, and treatment-related information was gathered to see if any of these factors are associated with depression. The study found that race/ethnicity, disease activity and medications are not associated with depression. The variables associated with depression are shorter disease duration and increased disability as scored on the Health Assessment Questionnaire.
Lead scientist Mary Margaretten, MD, says, RA affects people both physically and psychologically. Given that comorbid depressive symptoms are known to worsen health outcomes, it is useful to parse out the determinants of depression in patients with rheumatoid arthritis.
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